KOFF GO PLUS TABLETS

Tablets

KOFF GO PLUS TABLETS

PACKING:
60x20x10 tablets

COMPOSITION:
Each film coated tablet contains:
Cetirizine Hydrochloride  
I.P.  
5 mg
Ambroxol Hydrochloride  
I.P.  
60 mg
 
DESCRIPTION:
Ambroxol Hydrochloride is the metabolite of bromhexine and a mucolytic agent. Ambroxol acts as secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Cetirizine is a second-generation antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist.
 
MECHANISM OF ACTION:
Ambroxol facilitates mucociliary clearance by intensifying the motion of the cilia present on the ciliated respiratory epithelium. Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. It crosses the blood brain barrier only slightly, reducing the sedative side-effect common with older antihistamines.
 
INDICATIONS:
Seasonal/allergic rhinitis, nasal discomfort, body ache, stubborn cough.
 
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
 
WARNING:
Do not exceed recommended dosage.
 
DOSAGE:
As directed by the physician.
 
STORAGE:
Store in a cool & dry place. Protect from light.
 
PRESENTATION:
20x10 tablets in a cardboard carton