NEW COLD GO TABLETS

NEW COLD GO TABLETS

PACKING:
60x20x10 tablets

COMPOSITION:
Each uncoated tablet contains:
Cetirizine HCl
I.P
5 mg
Phenylephrine HCl
I.P.
10 mg
Paracetamol
I.P.
325 mg
Colour: Sunset yellow
:
 
DESCRIPTION:
COLD-GO tablets contains an analgesic-antipyretic Paracetamol with decongestant Phenylephrine. Paracetamol is a para-aminophenol derivative, produces antipyresis by acting on the hypothalamic heat regulating center and analgesia by elevating the pain threshold. Phenylephrine Hydrochloride is a selective α1-adrenergic receptor agonist used primarily as a decongestant. Cetirizine is a second-generation antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist.
 
MECHANISM OF ACTION:
Paracetamol works by blocking the action of a substance in the body called cyclooxygenase. Cyclooxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Phenylephrine constricts the blood vessels in the nasal mucous membranes and allows the air passages to open up. The majority of the sympathomimetic action is due to direct stimulation of the adrenoceptors. Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. It crosses the blood–brain barrier only slightly, reducing the sedative side-effect common with older antihistamines.
 
INDICATIONS:
Nasal and sinus congestion, sinus pain and headache, allergic symptoms of the nose or throat due to upper respiratory tract allergies.
 
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
 
SIDE EFFECTS:
Headache, dizziness, nausea, palpitations, restlessness.
 
DOSAGE:
As directed by the physician.
 
STORAGE:
Keep away from children. Store in a cool, dry place. Protect from light.
 
PRESENTATION:
20x10 tablets in a carton
 
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