NIMUMAC COLD TABLETS

Tablets

NIMUMAC COLD TABLETS

PACKING:
60x20x10 tablets

COMPOSITION:
Each uncoated tablet contains:
Nimesulide
B.P.
100 mg
Phenylephrine Hydrochloride     
I.P.    
5 mg
Chlorpheniramine Maleate
I.P.
4 mg
Caffeine (Anhydrous)
I.P.
30 mg
 
DESCRIPTION::
Nimesulide is an antipyretic & analgesic. Chlorpheniramine Maleate an alkylamine derivative is anti-histaminic that causes moderate degree of sedation. Phenylephrine is a decongestant. Caffeine is a mild stimulant.
 
MECHANISM OF ACTION:
Nimesulide is an inhibitor of cyclooxygenase so it inhibits synthesis of destructive prostaglandins and spares cytoprotective prostaglandins. Phenylephrine works by acting on alpha receptors that are found in the walls of blood vessels in the linings of the nasal passages and sinuses. It causes these blood vessels to contract and narrow, thereby decreasing blood flow into the linings of the nose and sinuses. This reduces the feeling of congestion and also reduces the production of mucus, helping to relieve a blocked nose. Chlorpheniramine maleate has sedative & anti-cholinergic actions, but lack selectivity for the cough centre. Caffeine is a mild stimulant that helps reduce fatigue.
 
INDICATIONS:
Body ache, pain, common cold and other allergic conditions.
 
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
 
SIDE EFFECTS:
Headache, dizziness, nausea, anxiety, restlessness.
 
WARNING:
Use of Nimesulide should ordinarily be restricted to 10 days. If longer clinical use is warranted, liver function test should be assessed periodically.
 
DOSAGE:
As directed by the physician.
Not for children below 12 years of age.
 
STORAGE:
Store in a cool, dry & dark place.
 
PRESENTATION:    20x10 tablets in a cardboard carton
 
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