NIMUMAC COLD TABLETS

Tablets

NIMUMAC COLD TABLETS

PACKING:
60x20x10 tablets

COMPOSITION:
Each uncoated tablet contains:
Nimesulide
B.P.
100 mg
Phenylephrine Hydrochloride   
I.P.    
5 mg
Levocetirizine Hydrochloride   
I.P.    
5 mg
Excipient
 
q.s.
 
DESCRIPTION::
Nimesulide is an antipyretic & analgesic. Phenylephrine is a decongestant. Levocetirizine, the (R) enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors.
 
MECHANISM OF ACTION:
Nimesulide is an inhibitor of cyclooxygenase so it inhibits synthesis of destructive prostaglandins and spares cytoprotective prostaglandins. Phenylephrine works by acting on alpha receptors that are found in the walls of blood vessels in the linings of the nasal passages and sinuses. It causes these blood vessels to contract and narrow, thereby decreasing blood flow into the linings of the nose and sinuses. This reduces the feeling of congestion and also reduces the production of mucus, helping to relieve a blocked nose. Levocetirizine works by blocking histamine receptors. It does not prevent the actual release of histamine from mast cells, but prevents binding it to its receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief.
 
INDICATIONS:
Body ache, pain, common cold and other allergic conditions.
 
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
 
SIDE EFFECTS:
Headache, dizziness, nausea, anxiety, restlessness.
 
WARNING:
Use of Nimesulide should ordinarily be restricted to 10 days. If longer clinical use is warranted, liver function test should be assessed periodically.
 
DOSAGE:
As directed by the physician.
Not for children below 12 years of age.
 
STORAGE:
Store in a cool, dry & dark place.
 
PRESENTATION:    20x10 tablets in a cardboard carton
 
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