OFLOXAMAC TABLETS

OFLOXAMAC TABLETS

PACKING:
80x4x50 tablets

COMPOSITION:
Each film coated tablet contains:
Ofloxacin    
I.P.    
200 mg
Excipients
 
q.s.
 
DESCRIPTION::
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its mirror image or enantiomer dextrofloxacin.
 
MECHANISM OF ACTION:
It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting bacterial cell division. It works by stopping the growth of bacteria.
 
INDICATIONS:
It is used to treat a variety of bacterial infections. This antibiotic treats only bacterial infections.
 
CONTRA-INDICATIONS:
Ofloxacin is considered to be contraindicated for the treatment of certain sexually transmitted diseases due to bacterial resistance. Caution in patients with liver disease. Ofloxacin is also considered to be contraindicated within the pediatric population, pregnancy, nursing mothers, patients with psychiatric illnesses and in patients with epilepsy or other seizure disorders.
 
SIDE EFFECTS:
Upset stomach, nausea, diarrhea, headache, dizziness, lightheadedness, or trouble sleeping may occur.
 
DRUG INTERACTIONS:
Corticosteroids, duloxetine, drugs to treat diabetes, live bacterial vaccines, nonsteroidal anti-inflammatory drugs, probenecid, theophylline, warfarin.
 
DOSAGE:
As directed by the physician.
 
STORAGE:
Store in a cool, dry place. Protect from light.
 
PRESENTATION:    4x50 tablets in a cardboard carton
 
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