OFLOXAMAC E/E DROPS

Eye/Ear Drops

OFLOXAMAC E/E DROPS

PACKING:
576x10ml

COMPOSITION:
Ofloxacin
I.P.
0.3% w/v
Benzalkonium Chloride Solution    
I.P.     
0.02% w/v
Sterile Aqueous Vehicle
 
q.s.
 
DESCRIPTION::
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its mirror image or enantiomer dextrofloxacin.
 
MECHANISM OF ACTION::
It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV,which is an enzyme necessary to separate replicated DNA, thereby inhibiting bacterial cell division.
 
INDICATIONS:
It is used to treat a variety of bacterial infections. It works by stopping the growth of bacteria, This antibiotic treats only bacterial infections.
 
CONTRA-INDICATIONS:
Caution in patients with liver disease. Ofloxacin is also considered to be contraindicated within the pediatric population, pregnancy, nursing mothers, patients with psychiatric illnesses and in patients with epilepsy or other seizure disorders.
 
SIDE EFFECTS:
Upset stomach, nausea, diarrhea, headache, dizziness, lightheadedness, or trouble sleeping may occur.
 
DRUG INTERACTIONS:
Corticosteroids (e.g., dexamethasone, prednisone), duloxetine, drugs to treat diabetes (e.g., glyburide, insulin), live bacterial vaccines, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), probenecid, theophylline, warfarin.
DOSAGE:
As directed by the physician.
 
DIRECTIONS:
Use the solution within one month after opening the container.
Do not use if the solution contains particles/suspended matter.
 
STORAGE:
Store in a cool, dry place. Protect from light.
 
PRESENTATION:    10ml plastic vial
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