DICLONICE CAPSULES

Capsules

DICLONICE CAPSULES

PACKING:
48x20x10 capsules

COMPOSITION:
Each capsule contains:
Nimesulide                   
B.P.           
       100 mg
Diclofenac Sodium
I.P.
         50 mg
 
DESCRIPTION:
Diclonice is a combination of Diclofenac , a Phenylacetic acid derivative and Nimesulide is chemically 4-Nitro-2-Phenoxymethane Sulfonanilide. These acts as anti-inflammatory and analgesic. Both belong to the category of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).
 
MECHANISM OF ACTION:
Nimesulide is an inhibitor of cyclooxygenase (COX), it inhibits synthesis of destructive prostaglandins and spares cytoprotective prostaglandins. Nimesulide appears to exert its effects also through a variety of other mechanisms and involves interference with the production action of mediators other than prostaglandins such as enzymes, toxic oxygen derivatives, cytokines, platelet activating factor and histamine. Diclofenac inhibits prostaglandin synthesis by interfering with the action of prostaglandin synthetase.
 
INDICATIONS:
Used to treat acute (short term) pain, inflammatory disorders.
 
CONTRA-INDICATIONS:
Hypersensitivity to any of the ingredients, GI bleeding, active peptic ulcer disease; severe renal and heart failure; hepatic impairment or known liver disease; coagulation disorders; pregnancy; children less than 12 years old.
 
SIDE-EFFECTS:
Diarrhoea, vomiting, skin rash, pruritis, dizziness, bitterness in mouth.
 
DOSAGE:
As prescribed by the physician.
 
STORAGE:
Store in a cool, dry & dark place. Keep all the medicines away from the children.
 
PRESENTATION:  20x10 capsules in a cardboard carton
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