PHENICOL SUSPENSION

Oral Liquids

PHENICOL SUSPENSION

PACKING:
200x60ml

COMPOSITION:
Each 5ml contains:
Chloramphenicol Palmitate          
I.P.
125 mg
Eq. to Chloramphenicol IP
 
 
In a flavoured syrupy base
 
 
DESCRIPTION::
Chloramphenicol Palmitate is a dichloroacetic acid derivative. Chloramphenicol is a broad-spectrum antibiotic and is bacteriostatic. It contains 55.5-59.5% of chloramphenicol i.e. approx. 174 mg Chloramphenicol Palmitate is equivalent to 100 mg Chloramphenicol.
 
MECHANISM OF ACTION::
Chloramphenicol is hydrolysed in theupper intestinal tract into the parentdrug. It is lipid soluble, diffuses through the bacterial cell membrane and reversibly binds to the 50 S subunit of bacterial ribosomes where transfer of amino acids to growing peptide chains is prevented, thus inhibiting peptide bond formation and subsequent protein synthesis.
 
INDICATIONS:
It is effective against broad spectrum bacterial (gram-positive and gram-negative) diseases.
 
CONTRA-INDICATIONS:
Chloramphenicol is contraindicated if another drug can be used instead due to its potential to cause bone marrow depression.
 
SIDE EFFECTS:
This medication may cause stomach upset, diarrhea, headache, nausea, and vomiting which should disappear in a few days as your body adjusts to the medication.
 
DRUG INTERACTIONS:
Diabetes medicine, warfarin, phenytoin, phenobarbital, rifampin, other antibiotics, vitamin B12, iron, folic acid. This drug may interfere with the effectiveness of birth control pills.
 
PRECAUTIONS & WARNING:
Blood dyscrasias may be associated with the use of chloramphenicol. It is essential that adequate blood studies be made. Use extreme caution when giving this drug to children less than 2 years old.
 

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DOSAGE:
As directed by the physician.
 
STORAGE:
Store in a cool, dry & dark place, NOT FOR CHILDREN BELOW 12 YEARS OF AGE.
 
SHAKE WELL BEFORE USE
 
PRESENTATION:    60ml bottle
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