DEXAMETHASONE INJECTION

Injections

DEXAMETHASONE INJECTION

PACKING:
432 x 20ml, 300 x 30ml

COMPOSITION:

Each ml contains:

Dexamethasone Sodium Phosphate
I.P.
 
Equ.to dexamethasone phosphate
 
4 mg
Methylparaben
I.P.
0.15% w/v
Propylparaben
I.P.
0.02% w/v
(As preservatives)
 
 
 
DESCRIPTION:
Dexamethasone is an anti-inflammatory 9-fluoro-glucocorticoid. Dexamethasone is a Corticosteroid. The mechanism of action of dexamethasone is as a Corticosteroid Hormone Receptor Agonist.
 
MECHANISM OF ACTION:
Dexamethasone Sodium Phosphate is a sodium phosphate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. Dexamethasone Sodium phosphate are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. They modify the body’s immune responses to diverse stimuli. Dexamethasone sodium phosphate injection has a rapid onset but short duration of action when compared with less soluble preparations.
 
INDICATIONS:
It used to treat a number of conditions including arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders.
 
CONTRAINDICATIONS:
Do not use in viral infections. Except when used for emergency therapy. Existence of congestive heart failure, osteoporosis and diabetes are relative contraindications.
 
SIDE EFFECTS:
Swelling, redness, pain, or soreness at the injection site may occur. May also infrequently cause loss of appetite, nausea, vomiting, diarrhea, or headache.
 
DOSAGE:
As directed by the physician.
 
STORAGE:
Keep out of reach of the children Store below 25⁰C. Protect from light.
 
FOR IM/IV USE ONLY
PRESENTATION:
1 × 20 ml Vial, 1 x 30 ml Vial
 
0108906044106116 0118906044106113 0128906044106110
0108906044106123 0118906044106120 0128906044106127