TOPIBACT OINTMENT

External Preparations

TOPIBACT OINTMENT

PACKING:
432x5g

COMPOSITION:
Mupirocin
I.P.
2.0% w/w
In a non-greasy base
 
 
 
DESCRIPTION:
Mupirocin is a topical antibacterial agent, active against those organisms responsible for the majority of skin infections. It is also active against Gram-negative organisms such as Escherichia coli and Haemophilus influenzae.
 
MECHANISM OF ACTION:
Mupirocin is a novel antibiotic produced through fermentation by Pseudomonas fluorescens. Mupirocin inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally.
 
INDICATIONS:
Mupirocin Ointment is used for skin infections, e.g. impetigo, folliculitis, furunculosis.
 
DIRECTION FOR USE:
Apply gently on affected area or as directed by the physician.
 
CONTRA-INDICATIONS:
Hypersensitivity to the active substance(s) or to any of the excipients. This Mupirocin Ointment formulation is not suitable for ophthalmic or intranasal use.
 
SIDE EFFECTS:
Systemic allergic reactions including anaphylaxis, generalised rash, urticaria and angioedema have been reported with Mupirocin Ointment. Burning localised to the area of application. Itching, erythema, stinging and dryness localised to the area of application. Cutaneous sensitisation reactions to mupirocin or the ointment base
 
PRECAUTIONS:
Mupirocin Ointment is not suitable for ophthalmic use, intranasal use (in neonates or infants), use in conjunction with cannulae, at the site of central venous cannulation. Avoid contact with the eyes. If contaminated, the eyes should be thoroughly irrigated with water until the ointment residues have been removed.
 
STORAGE:
Store at a temperature not exceeding 25o C. Protect from light. Do not freeze
 
PRESENTATION:
5g tube.
 
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