PANTOMAC-DSR CAPSULE

Capsules

PANTOMAC-DSR CAPSULE

PACKING:
20x10 Capsules

COMPOSITION:
Each hard gelatin capsule contains:
Pantoprazole sodium
eqv. to pantoprazole
I.P.
40 mg
(as enteric coated pellets)
Domperidone
I.P.
30 mg
(as sustained release pellets)
 
Excipients
 
q.s.
 
DESCRIPTION:
Pantomac-DSR contains Pantoprazole which is a substituted benzimidazole proton pump inhibitor and Domperidone is an antidopaminergic agent.
 
MECHANISM OF ACTION:
Pantoprazole inhibits the H+/K+ ATPase enzyme, which is responsible for gastric acid secretion in the parietal cells of the stomach and irreversibly block the final step of acid secretion. It increases motility of GI tract by inhibiting the action of dopamine and fastens gastric emptying. Domperidone stimulates GI activity by acting as a competitive antagonist at dopamine D2-receptor.
 
INDICATIONS:
Dyspepsia and Gastro-esophageal reflux disease (GERD).
 
CONTRAINDICATIONS:
Pantoprazole is contraindicated in hepatic impairment; hypersensitivity. Domperidone is contraindicated in the history of hypersensitivity to dimenhydrinate or related compounds.
 
SIDE EFFECTS:
Headache, dizziness, diarrhea, rash, swelling.
 
DOSAGE:
As directed by the physician.
 
DIRECTIONS FOR USE:
Swallow pantoprazole tablets whole with a drink of water, Do not chew. Take each dose an hour before a meal. Take pantoprazole at around the same time every day.
 
STORAGE:
Store in a cool, dry place, protect from light.
 
PRESENTATION:
20x10 capsules in a cardboard carton.