KOFF GO PLUS TABLETS


KOFF GO PLUS TABLETS

Ambroxol Hydrochloride is the metabolite of bromhexine and a mucolytic agent. Ambroxol acts as secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Cetirizine is a second-generation antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of hydroxyzine and a racemic selective H1 receptor inverse agonist.

Category:

Product Description

PACKING:
60x20x10 tablets

COMPOSITION:
Each film-coated tablet contains:
Cetirizine Hydrochloride
I.P.
5 mg
Ambroxol Hydrochloride
I.P.
60 mg
DESCRIPTION:
Ambroxol Hydrochloride is the metabolite of bromhexine and a mucolytic agent. Ambroxol acts as secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Cetirizine is a second-generation antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of hydroxyzine and a racemic selective H1 receptor inverse agonist.
MECHANISM OF ACTION:
Ambroxol facilitates mucociliary clearance by intensifying the motion of the cilia present on the ciliated respiratory epithelium. Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. It crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines.
INDICATIONS:
Seasonal/allergic rhinitis, nasal discomfort, body ache, stubborn cough.
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
WARNING:
Do not exceed recommended dosage.
DOSAGE:
As directed by the physician.
STORAGE:
Store in a cool & dry place. Protect from light.
PRESENTATION:
20×10 tablets in a cardboard carton


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