ACTIPAR SYRUP

DESCRIPTION: Actipar Syrup contains Piperazine, an anthelminthic that expels parasitic worms (helminths) from the body. It is especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children.

DOSAGE FORM: Syrup

ROUTE OF ADMINISTRATION: Oral

COMPOSITION:

Each 5ml contains:

Excipients: Sunset Yellow, Tartrazine Supra, Aspartame, Citric Acid (Monohydrate), Glycerin, Methyl Paraben Sodium, Propyl Paraben Sodium, Sorbitol Solution, Orange Flavour (Liquid)

MECHANISM OF ACTION: Piperazine is a GABA receptor agonist. Piperazine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

INDICATIONS: Piperazine is indicated as an alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm).

DOSAGE: As prescribed by the physician.

SIDE-EFFECTS: The blurring of vision (in rare cases), hypersensitivity (fever, joint pain, skin rash or itching).

CONTRAINDICATIONS: Hypersensitivity reactions to piperazine and its salts.

DRUG INTERACTIONS: Phenothiazines, high doses of piperazine may enhance the effects of phenothiazines, such as chlorpromazine, and increase the risk of seizures; concurrent use is not recommended.

PRECAUTIONS & WARNING: Regular visits to the physician to check progress, checking with the physician if no improvement after the full course of treatment or if symptoms persist.

STORAGE: Store in a cool & dark place.

SHAKE WELL BEFORE USE

PRESENTATION: 144x30ml