Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered second-generation fluoroquinolone. Ofloxacin is a racemic mixture consisting of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.
Each 5ml contains:
MECHANISM OF ACTION:
It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, an enzyme necessary to separate replicated DNA, thereby inhibiting bacterial cell division.
It is used to treat a variety of bacterial infections. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections.
Ofloxacin is considered to be contraindicated for the treatment of certain sexually transmitted diseases due to bacterial resistance. Caution in patients with liver disease. Ofloxacin is also contraindicated within the pediatric population, pregnancy, nursing mothers, patients with psychiatric illnesses, and patients with epilepsy or other seizure disorders.
Upset stomach, nausea, diarrhea, headache, dizziness, lightheadedness, or trouble sleeping may occur. A severe allergic reaction to this drug is rare.
Corticosteroids, duloxetine, drugs to treat diabetes (e.g., glyburide, insulin), nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), probenecid, theophylline, warfarin.
As directed by the physician.
Store in a cool, dry place. Protect from light.