COMPOSITION:
Each 5ml contains:
Dried Aluminium Hydroxide Gel BP 400mg
Magnesium Hydroxide BP 400mg
Simethicone USP 50mg
In flavoured sorbitol base
Colour: Erythrosine
MECHANISM OF ACTION: Aluminium Hydroxide acts on the Hydrochloric acid in the stomach by neutralization, forming Aluminium Chloride salt and water. Magnesium Hydroxide increases peristaltic activity causing osmotic retention of f luids, thus resulting in bowel evacuation. It also reduces stomach acidity by reacting with Hydrochloric acid to form Magnesium Chloride. Simethicone lowers surface tension and facilitates gas dispersion by causing coalescence of gas bubbles in the GI tract, thus helping in their dispersion.
INDICATIONS: Polygel is used in gastrointestinal disorders manifested with the hyper acidity and increased gas production. May be administered as mono therapy or in the treatment of gastro-oesophagitis reflux, chronic diarrhoea, and non-ulcer dyspepsia.
CONTRAINDICATIONS: In patients with renal insufficiency because of the risk of increase of Magnesium and Aluminium serum concentration due to the decreased excretion through the kidneys. Do not use in patients allergic to Magnesium and Aluminium.
SIDE EFFECTS: Nausea, constipation may occur in some patients.
DRUG INTERACTIONS: No drug interactions are known. There is no evidence that simethicone modifies the effects of other drugs.
PRECAUTIONS & WARNING: Extensive use of Aluminium-containing antacids may cause hypophosphatemia (low phosphate levels in the blood), which in severe cases could lead to muscle weakness, anorexia, and osteomalacia (softening of the bones due to defective bone mineralization).
DOSAGE: As directed by the Physician.
STORAGE: Store at a temperature not exceeding 30°C. Protect from light.
PACKAGING: 160 ml bottle in a duplex board carton.