DESCRIPTION: Trixone Plus Injection is a combination of a beta-lactam antibiotic- Ceftriaxone with an inhibitor of beta lactamase-Sulbactam sodium, giving a highly powerful antibacterial formulation. ?Ceftriaxone is a third-generation cephalosporin antibiotic, Sulbactam sodium is a derivative of the basic penicillin nucleus. PACKING: 12x12x1.5g vial
COMPOSITION:
Each vial contains:
Part I |
||
Ceftriaxone Sodium Sterile |
U.S.P |
1g |
equi. to Ceftriaxone |
||
Salbactum Sodium |
U.S.P |
500mg |
equi. to Salbactum |
||
Part II |
||
Water for Injection |
B.P. |
10ml |
MECHANISM OF ACTION: Ceftriaxone inhibits the third and final stage of bacterial cell wall synthesis by preferentially binding to the specific PBPs located inside the bacterial cell wall. Ceftriaxone interferes with PBP-mediated cell wall synthesis leading to cell lysis and death. Sulbactam, by irreversibly binding to the beta-lactamases produced by the bacteria protects the beta-lactam ring of ceftriaxone and conserves the activity. The combination helps extend its utility in the treatment of a broad range of infections caused by organisms resistant to the antibiotic alone. INDICATIONS: Renal and urinary tract infections, skin and soft tissue infections, infections in a dialysis unit. CONTRAINDICATIONS: Contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Hypersensitivity to penicillin may predispose the patient to the possibility of allergic cross-reactions. SIDE EFFECTS: Diarrhoea, nausea & vomiting, headache, dizziness, increase in serum creatinine. DOSAGE: As prescribed by the physician. STORAGE: Store below 25℃. Protect from light and moisture. FOR IM/IV USE ONLY PRESENTATION: 1.5gm vial BARCODE:
0108906044107656 0118906044107653 0128906044107650