Description: Torque’s Rabitor-DSR capsules is a medication in sustained release pellets form combining rabeprazole, a proton pump inhibitor, and domperidone, a prokinetic agent, to treat conditions related to excessive stomach acid and gastrointestinal motility disorders.
Pharmaceutical Dosage Form: Capsule
Route of Administration: Oral
Composition: Each hard gelatin capsule contains:
| Rabeprazole Sodium (as enteric coated pellets) |
I.P. |
20mg |
| Domperidone (as sustained release pellets) |
I.P. |
30mg |
| Excipients |
|
q.s. |
Mechanism of Action: Rabeprazole, a proton pump inhibitor (PPI), works by irreversibly inhibiting the enzyme H+/K+ ATPase in the stomach lining. This enzyme is responsible for the final step in the production of gastric acid. By blocking H+/K+ ATPase, rabeprazole reduces the secretion of stomach acid, leading to a decrease in acidity levels. Domperidoneis a dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. It provides relief from nausea by blocking receptors at the chemoreceptor trigger zone. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach.
Indications: Torque’s Rabitor-DSR capsules is used to treat gastro-esophageal reflux disease (GERD), acidity, and indigestion.
Dosage: As prescribed by the physician.
Storage: Store protected from light & moisture, at a temperature not exceeding 25ºC.
Presentation: 20 x 10 capsules
Side effects:
Flatulence
Headache
Stomach pain
Dry mouth
Diarrhea
Contraindications: Torque’s Rabitor-DSR capsule is contraindicated in patients with a history of hypersensitivity to the drug or any excipients from the dosage form.
Drug Interactions: Torque’s Rabitor-DSR capsule can interact with other drugs. Here are some notable drug interactions:
Atazanavir
Nelfinavir
Digoxin
Saquinavir
Warfarin
Methotrexate
Aspirin
Cyanocobalamin
ADR: Proton pump inhibitors can cause acute Kidney injury as an adverse drug reactions.
