Product Description
Description: Torque’s Uditor 300 Tablets contains ursodeoxycholic acid which is a naturally occurring hydrophilic bile acid, derived from cholesterol and is present as a minor fraction of the total human bile acid pool.
Pharmaceutical Dosage Form: Tablet
Route of Administration: Oral
Composition: Each uncoated tablet contains:
Ursodeoxycholic Acid IP……… 300 mg
Excipients………………………………. q.s
Mechanism of Action: Oral administration of ursodeoxycholic acid increases its fraction in a dose related manner, to become the major biliary acid, replacing/displacing toxic concentrations of endogenous hydrophobic bile acids that tend to accumulate in cholestatic liver disease. In addition to the replacement and displacement of toxic bile acids, other mechanisms of action include cytoprotection of the injured bile duct epithelial cells (cholangiocytes) against toxic effects of bile acids, inhibition of apoptosis of hepatocytes, immunomodulatory effects, and stimulation of bile secretion by hepatocytes and cholangiocytes.
Indications: Torque’s Uditor 300 is indicated in the treatment of patients with
Cholestatic liver disease
Primary Biliary Cholangitis
Primary Biliary Cirrhosis
Gallbladder stones
Dosage: As directed by the physician.
Storage: Store at a temperature not exceeding 30°C, protect from light & moisture.
Presentation: 5 x 3 x 15 Tablets
Side effects:
Diarrhea
Nausea/Vomiting
Right Upper Abdominal Pain
Exacerbation of Pruritus
Contraindications: Torque’s Uditor 300 is contraindicated in patients with a known allergy to bile acids or excipients, Patients with compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary-gastrointestinal fistula and patients with calcified cholesterol stones, radiopaque stones, or radiolucent bile pigment stones are not candidates for Ursodeoxycholic acid therapy.
Drug Interactions: Torque’s Uditor 300 can cause drug interaction with following drugs:
Bile acid sequestering agents such as cholestyramine and colestipol
Aluminum-based antacids
Estrogens, oral contraceptives, and clofibrate (and perhaps other lipid lowering drugs)
