FIXIMAC-O TABLET

Categories: ,

Product Description

Description: Fiximac-O Tablet combines Cefixime and Ofloxacin to effectively treat a range of bacterial infections, including respiratory, urinary, and gastrointestinal infections. It works by inhibiting bacterial growth and preventing DNA replication.

Pharmaceutical Dosage Form: Tablet

Route of Administration: Oral

Composition: Each film coated tablet contains:

Cefixime (as Trihydrate)                               I.P.

Eq. to Anhydrous Cefixime                                             200mg

Ofloxacin                                                       I.P.             200mg

Excipients                                                                              q.s.

Colour: Tartrazine & Titanium Dioxide I.P.

Mechanism of Action: Cefixime exerts its antibacterial action by inhibiting the synthesis of bacterial cell walls through binding to penicillin-binding proteins, disrupting the formation of the cell wall and leading to bacterial cell death. Ofloxacin inhibits bacterial DNA replication by inhibiting bacterial topoisomerases, particularly DNA gyrase and topoisomerase IV.

Indications: Fiximac-O Tablet is used for the treatment of patients with typhoid fever and urinary tract infection in adults.

Dosage: As prescribed by the physician.

Storage: Protect from light and store below 300

Presentation: 10X1X10 Tablets

Side effects:

Nausea

Abdominal pain

Allergy

Diarrhea

Stomach pain

Contraindications: Fiximac-O Tablet is contraindicated in patients with a known allergy to Cefixime/ Ofloxacin or to the Cephalosporin/ fluoroquinolone group of antibiotics.

Drug Interactions: Fiximac-O Tablet can interact with other drugs, potentially affecting their efficacy or increase the risk of side effects. Some notable drug interactions include –

Cefixime:

BCG Vaccine live

Cholera vaccine

Typhoid live vaccine

Antacids and H2 blockers

Probenecid

Nephrotoxic drugs

Warfarin

Oral contraceptives

          Ofloxacin

Antacids, Sucralfate, Metal Cations

Theophylline, fenbufen or similar non-steroidal anti-inflammatory drugs

Antiarrhythmics, Tricyclic Antidepressants, macrolides, and antipsychotics

Probenecid, cimetidine, furosemide, and methotrexate

Vitamin K antagonists