Nortor-TZ Tablets

Product Description

Description: Nortor-TZ Tablets contain Norfloxacin is a broad-spectrum antibacterial agent and tinidazole is a synthetic antiprotozoal and antibacterial agent that are used to treat diarrhea and dysentery.

Pharmaceutical Dosage Form: Tablet

Route of Administration: Oral

Composition:

Mechanism of Action: Norfloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase, an enzyme essential for DNA replication, transcription, repair, and recombination in bacteria. By inhibiting DNA gyrase, Norfloxacin interferes with the process of bacterial DNA synthesis and leads to the death of susceptible bacteria. Tinidazole inhibits the growth of protozoa by interacting with the DNA of the micro-organism and inhibiting the protein synthesis, thereby leading to death of the micro-organism.

Indications: Nortor-TZ Tablets are indicated for the treatment of diarrhoea and dysentery of amoebic, bacterial or mixed origins.

Dosage: As prescribed by the physician.

Storage: Store at a temperature not exceeding 25°C. Protect from light and moisture.

Presentation: 10 x 4 x 10 Tablets

Side effects:

Dizziness

Nausea

Headache

Abdominal Cramping

Weakness

Fatigue

Malaise

Anorexia

Diarrhoea

Contraindications:

In patients with a history of hypersensitivity, tendinitis, or tendon rupture associated with the use of norfloxacin or any member of the quinolone group of antimicrobial and tinidazole or other nitroimidazole derivatives.

In pregnancy and during lactation

In patients having, or with a history of, blood dyscrasia, although no persistent haematological abnormalities have been noted in clinical or animal studies.

Drug Interactions: Nortor-TZ tablets should not be taken with the following medicines due to severe side effects –

Caffeine

Clozapine

Ropinirole

Tacrine

Tizanidine

Theophylline

Cyclosporine

Anticoagulants

Glyburide

Probenecid

Nitrofurantoin

Alcohol, Disulfiram

Phenytoin, Fosphenytoin

Cyclosporine, Tacrolimus