Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its mirror image or enantiomer dextrofloxacin.
MECHANISM OF ACTION:
It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting bacterial cell division. It works by stopping the growth of bacteria.
It is used to treat a variety of bacterial infections. This antibiotic treats only bacterial infections.
Ofloxacin is considered to be contraindicated for the treatment of certain sexually transmitted diseases due to bacterial resistance. Caution in patients with liver disease. Ofloxacin is also considered to be contraindicated within the pediatric population, pregnancy, nursing mothers, patients with psychiatric illnesses and patients with epilepsy or other seizure disorders.
Upset stomach, nausea, diarrhoea, headache, dizziness, lightheadedness, or trouble sleeping may occur.
Corticosteroids, duloxetine, drugs to treat diabetes, live bacterial vaccines, nonsteroidal anti-inflammatory drugs, probenecid, theophylline, warfarin.
As directed by the physician.
Store protected from light and moisture.
80x4x50 tablets in a shipper
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