ORTHOMAC GEL


ORTHOMAC GEL

Orthomac gel contains Diclofenac diethylamine which is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Linseed oil is rich in alpha-linolenic acid (ALA). ALA belongs to a group of a substance called omega-3 fatty acid which helps to reduce inflammation. Methyl Salicylate acts as a counter rubefacient by stimulating the superficial afferent nerves from the same spinal segments that supply the painful muscles. Menthol has some local anaesthetic and counterirritant qualities and also acts as a weak kappa opioid receptor agonist making it an analgesic as well.

Product Description

PACKING:
12x30g

COMPOSITION:

Each g contains:

Diclofenac diethylamine
I.P
1.16% w/w
Equ. To Diclofenac Sodium
1% w/w
Linseed oil
B.P.
3% w/w
Methyl Salicylate
I.P.
10% w/w
Menthol
I.P.
5% w/w
Benzyl Alcohol
I.P.
1% w/w
(As Preservative)
In a gel base
q.s.
DESCRIPTION:
Orthomac gel contains Diclofenac diethylamine which is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Linseed oil is rich in alpha-linolenic acid (ALA). ALA belongs to a group of a substance called omega-3 fatty acid which helps to reduce inflammation. Methyl Salicylate acts as a counter rubefacient by stimulating the superficial afferent nerves from the same spinal segments that supply the painful muscles. Menthol has some local anaesthetic and counterirritant qualities and also acts as a weak kappa opioid receptor agonist making it an analgesic as well.

MECHANISM OF ACTION:
Diclofenac acts by reducing the inflammation by inhibiting the COX-isoenzyme and thereby decreasing the synthesis of pro-inflammatory prostaglandins. At high tissue concentration Diclofenac appears to have the capacity to act as a sodium channel blocker to mediate local-anaesthetic like effects on nociceptive afferent fibres. Linseed oil helps to reduce inflammation in distinct phases, firstly an acute phase of local vasodilatation and increased capillary permeability. Methyl Salicylate is topically used to cause dilation of the capillaries thereby increasing blood flow to the area. Menthol has the ability to chemically trigger the cold-sensitive TRPM8 receptors in the skin is responsible for its cooling sensation when applied to the skin. It enhances the efficacy of other topical applications by increasing penetration via vasodilation.

DOSAGE:
As directed by a physician

INDICATIONS:
Sprain, Backache, Muscular pain, Soft tissue injuries, musculoskeletal disorders.

CONTRAINDICATIONS:
Contraindicated in patients with known hypersensitivity to diclofenac or any components of the drug product.

ADVERSE EVENTS:
Local skin reactions, Hypersensitivity reactions.

STORAGE:
Store in a cool & dry place. Do not freeze.

PRESENTATION:
30 g tube

FOR EXTERNAL USE ONLY

BARCODE:
0118906044108087
0128906044108084


Leave a Reply

Your email address will not be published.