Product Description
Description: Torformin 1000 SR Tablets contains Metformin, a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose.
Pharmaceutical Dosage Form: Tablet
Route of Administration: Oral
Composition:
Each uncoated prolonged release tablet contains:
Metformin Hydrochloride IP 1000 mg
Excipients q.s.
Mechanism of Action: Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Indications: Torformin 1000 SR is indicated for the treatment of patients with type II diabetes mellitus when diet, exercise and single agent does not result in adequate glycemic control.
Dosage: As directed by the physician.
Storage: Store at a temperature not exceeding 30°C, protected from light & moisture.
Presentation: 20 x 10
Side effects: The following adverse reactions may occur:
Lactic Acidosis
Taste Disturbance
Nausea
Vomiting
Diarrhoea
Abdominal Pain
Loss of Appetite
Contraindications:
Torformin 1000 SR is contraindicated in patients with:
Known hypersensitivity to metformin or any of the components of this product.
Severe renal impairment
Acute conditions with the potential to alter renal function such as:
– dehydration,
– severe infection,
– shock
Disease which may cause tissue hypoxia
Decompensated Heart Failure
Respiratory Failure
Recent Myocardial Infarction
Shock
Hepatic insufficiency, acute alcohol intoxication, alcoholism
Drug Interactions:
Alcohol
NSAIDs
ACE Inhibitors
Angiotensin II Receptor Antagonists
Diuretics
Verapamil
Rifampicin
Cimetidine, Dolutegravir, Ranolazine, Trimethoprime,
Isavuconazole,
Vandetanib, Crizotinib, Olaparib
