Torque's Glimtor M2 Tablets

Description: Torque’s Glimtor M2 Tablets contain Metformin, a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose and Glimepiride, a sulphonylurea antihyperglycaemic agent acts mainly by stimulating insulin release from pancreatic beta cells. Pharmaceutical Dosage Form: Tablet Route of Administration: Oral Composition:

Mechanism of Action: Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Glimepiride primarily lowers blood glucose by stimulating the release of insulin from pancreatic beta-cells. It binds to the sulphonylurea receptor in the pancreatic beta-cell plasma membrane, leading to closure of the ATP-sensitive potassium channel, thereby stimulating the release of insulin. Indications: Torque’s Glimtor M2 Tablets are indicated for the treatment of patients with type II diabetes mellitus when diet, exercise and single agent does not result in adequate glycemic control. Dosage: As directed by the physician. Storage: Store protected from light & moisture, at a temperature not exceeding 30°C. Presentation: 10 x 15 Tablets Side effects: The following adverse reactions may occur: Lactic Acidosis Taste Disturbance Nausea Vomiting Diarrhoea Abdominal Pain Loss of Appetite Contraindications: Torque’s Glimtor M2 Tablets are contraindicated in patients with: Known hypersensitivity to metformin, glimepiride or any of the components of this product. Severe renal impairment Acute or chronic metabolic acidosis, including diabetic ketoacidosis and lactic acidosis Diabetic pre-coma An allergic reaction to sulphonamide derivatives may develop an allergic reaction Hepatic insufficiency, acute alcohol intoxication, alcoholism Insulin dependent diabetes Drug Interactions: Alcohol NSAIDs ACE Inhibitors Angiotensin II Receptor Antagonists Diuretics Verapamil Rifampicin Cimetidine, Dolutegravir, Ranolazine, Trimethoprime Isavuconazole, Fluconazole Vandetanib, Crizotinib, Olaparib Thyroid Stimulating Agents, Glucocorticoids Anabolic Steroids and Male Sex Hormones