Description: Torque’s Uditor 300 Tablets contain ursodeoxycholic acid which is a naturally occurring hydrophilic bile acid, derived from cholesterol and is present as a minor fraction of the total human bile acid pool. Pharmaceutical Dosage Form: Tablet Route of Administration: Oral Composition: Each uncoated tablet contains: Ursodeoxycholic Acid IP......... 300 mg Excipients..................................... q.s. Mechanism of Action: Oral administration of ursodeoxycholic acid increases its fraction in a dose related manner, to become the major biliary acid, replacing/displacing toxic concentrations of endogenous hydrophobic bile acids that tend to accumulate in cholestatic liver disease. In addition to the replacement and displacement of toxic bile acids, other mechanisms of action include cytoprotection of the injured bile duct epithelial cells (cholangiocytes) against toxic effects of bile acids, inhibition of apoptosis of hepatocytes, immunomodulatory effects, and stimulation of bile secretion by hepatocytes and cholangiocytes. Indications: Torque’s Uditor 300 Tablets are indicated in the treatment of patients with: Cholestatic liver disease Primary biliary cholangitis Primary biliary cirrhosis Gallbladder stones Dosage: As directed by the physician. Storage: Store at a temperature not exceeding 30°C, protect from light & moisture. Presentation: 5 x 3 x 15 Tablets Side effects: Diarrhea Nausea/ vomiting Right upper abdominal pain Exacerbation of pruritus Contraindications: Torque’s Uditor 300 Tablets are contraindicated in patients with a known allergy to bile acids or excipients, Patients with compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary-gastrointestinal fistula and patients with calcified cholesterol stones, radiopaque stones, or radiolucent bile pigment stones are not candidates for Ursodeoxycholic acid therapy. Drug Interactions: Torque’s Uditor 300 Tablets can cause drug interaction with following drugs: Bile acid sequestering agents such as cholestyramine and colestipol Aluminum-based antacids Estrogens, oral contraceptives, and clofibrate (and perhaps other lipid lowering drugs)